Conduct Disorder is defined as a behavior disorder of childhood or adolescence characterized by a pattern of conduct in which either the basic rights of others or the societal norms or rules appropriate for a certain age are violated.

Conduct Disorder is present in approximately 9% of boys and 2–9% of girls under the age of 18. Children with conduct disorder act out aggressively and express anger inappropriately. They engage in a variety of antisocial and destructive acts, including violence towards people and animals, destruction of property, lying, stealing, truancy, and running away from home. They often begin using and abusing drugs and alcohol, and having sex at an early age. Irritability, temper tantrums, and low self-esteem are common personality traits of children with CD.

Conduct Disorder Programs

Zalvari™: (formerly SPN810)

• Being developed for serious conduct problems in the setting of ADHD.
  
• New indication for a currently marketed product.
  
• There are no currently approved therapies for this indication in the US.
  
• Phase II POC results were positive with plans to enter later stage clinical development in 2010.